Etoricoxib-d3

• CAT Number: R048590
• CAS Number: 850896-71-8
• Molecular Formula: C18H15ClN2O2S
• Molecular Weight: 361.85
• Purity: ≥95%
• Synonyms: 5-Chloro-6’-methyl-3-[4-(methylsulfonyl)phenyl]-2,3’-bipyridine-d3; Algix-d3; Arcoxia-d3; Etobrix-d3; Etocox-d3; Etoxib-d3; Etropain-d3; Kingcox-d3; MK 0663-d3; MK 663-d3; Tauxib-d3; Torcoxia-d3
• Storage: -20°C
• IUPAC Name: 5-chloro-2-(6-methylpyridin-3-yl)-3-[4-(trideuteriomethylsulfonyl)phenyl]pyridine
• InChI: InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3/i2D3
• InChIKey: MNJVRJDLRVPLFE-BMSJAHLVSA-N
• SMILES: [2H]C([2H])([2H])S(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)Cl)C3=CN=C(C=C3)C

Etoricoxib-d3（Cat No.:R048590） is a deuterated form of etoricoxib, a selective COX-2 inhibitor used in the treatment of arthritis and pain management. Enhanced with three deuterium atoms, this compound provides improved metabolic stability and analytical detectability, facilitating detailed pharmacokinetic and pharmacodynamic studies. Etoricoxib-d3 is particularly valuable for understanding the drug’s metabolism and for identifying potential metabolites in clinical research. Its use ensures more accurate measurements in mass spectrometry, helping researchers and healthcare professionals optimize therapeutic strategies and minimize side effects in the management of chronic pain and inflammatory conditions.