For research use only. Not for therapeutic Use.
<p>It is a substance which presents an estrogenic activity and sedative effects.</p><br />Lignan<!–C<SUB>22</SUB>H<SUB>26</SUB>O<SUB>6</SUB>–>, from plants of the Rutaceae Family</br><p>Eudesmine presents a short acting estrogenic activity and a sedative effect. <br>1.5 and 10 mg/kg cause a mass increase of the uterus in non-pubescent rats and induces oestrus in ovarectomized pubescent rats. <br>50 and 100 mg/kg cause a general relaxation of the animals and extends by 2.5 times the effects of soporifics. <br>100, 200 and 500 mg/kg present no effect on the convulsant activity of Caffeine (300 mg/kg), Corazole (Pentylenetrazole) (75 mg/kg) and Strychnine (1 mg/kg).</p></br>
| Catalog Number | R020150 |
| CAS Number | 526-06-7 |
| Molecular Formula | C22H26O6 |
| Purity | ≥95% |
| Target | Ribosomal S6 Kinase (RSK) |
| Reference | – Whiting. Natural Products Reports (1985). 2:195<br /><br />- Atal et al., Am. Journ. Chem. Soc. (1967). (c) 2228<br /><br /><br /><br /> |
