For research use only. Not for therapeutic Use.
Eupalinolide O is a sesquiterpene lactone with anticancer activities. Eupalinolide O induces cell apoptosis in human MDA-MB-468 breast cancer cells[1].
Eupalinolide O could induce cell cycle arrest and apoptosis in human MDA-MB-468 breast cancer cells. Eupalinolide O also shows anti-TNBC (triple-negative breast cancer) activity against human MDA-MB-468 breast cancer cells[1].
| Catalog Number | I044824 |
| CAS Number | 2170228-67-6 |
| Synonyms | [(3aR,4R,6E,9R,10E,11aR)-9-acetyloxy-6-formyl-10-methyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E)-4-hydroxy-2-methylbut-2-enoate |
| Molecular Formula | C22H26O8 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H26O8/c1-12(7-8-23)21(26)29-19-10-16(11-24)5-6-17(28-15(4)25)13(2)9-18-20(19)14(3)22(27)30-18/h5,7,9,11,17-20,23H,3,6,8,10H2,1-2,4H3/b12-7+,13-9+,16-5+/t17-,18-,19-,20+/m1/s1 |
| InChIKey | MAIWERGSXNNKMK-INSNYMJASA-N |
| SMILES | CC1=CC2C(C(CC(=CCC1OC(=O)C)C=O)OC(=O)C(=CCO)C)C(=C)C(=O)O2 |
| Reference | [1]. Bo Yang, et al. Precise discovery of a STAT3 inhibitor from Eupatorium lindleyanum and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485. |
