For research use only, not for therapeutic use.
Eupatilin（Cat No.:I002723）is a natural flavonoid derived from Artemisia species, known for its potent anti-inflammatory, antioxidant, and anti-cancer properties. It exerts its effects by inhibiting pro-inflammatory cytokines, reducing oxidative stress, and modulating key signaling pathways like NF-κB and MAPK. Eupatilin has shown promise in treating gastric disorders, such as gastritis and ulcers, due to its protective effects on gastric mucosa. Additionally, it has been studied for its anticancer activity in various tumor models. Eupatilin is widely used in pharmaceutical research for its potential therapeutic applications.
| Catalog Number | I002723 |
| CAS Number | 22368-21-4 |
| Synonyms | NSC 122413 |
| Molecular Formula | C18H16O7 |
| Purity | ≥95% |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one |
| InChI | InChI=1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3 |
| InChIKey | DRRWBCNQOKKKOL-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)OC)O)OC |
| Reference | <p style=/line-height:25px/> <br>[2]. Yu K, et al. Eupatilin protects against tumor necrosis factor-α-mediated inflammation inhuman umbilical vein endothelial cells. Int J Clin Exp Med. 2015 Dec 15;8(12):22191-7. <br>[3]. Jeong JH, et al. Eupatilin Exerts Antinociceptive and Chondroprotective Properties in a Rat Model of Osteoarthritis by Downregulating Oxidative Damage and Catabolic Activity in Chondrocytes. PLoS One. 2015 Jun 17;10(6):e0130882. </p> |
