Euphorbia Factor L2

• CAT Number: I017698
• CAS Number: 218916-51-9
• Molecular Formula: C₃₈H₄₂O₉
• Molecular Weight: 642.73
• Purity: ≥95%
• Target: Apoptosis
• Storage: 4°C, protect from light
• IUPAC Name: [(1R,3Z,5R,7S,9R,11R,12R,13S,14S)-1,11-diacetyloxy-13-benzoyloxy-3,6,6,14-tetramethyl-10-methylidene-2-oxo-9-tricyclo[10.3.0.05,7]pentadec-3-enyl] benzoate
• InChI: InChI=1S/C38H42O9/c1-21-18-28-29(37(28,6)7)19-30(45-35(42)26-14-10-8-11-15-26)23(3)33(44-24(4)39)31-32(46-36(43)27-16-12-9-13-17-27)22(2)20-38(31,34(21)41)47-25(5)40/h8-18,22,28-33H,3,19-20H2,1-2,4-7H3/b21-18-/t22-,28+,29-,30+,31+,32-,33-,38+/m0/s1
• InChIKey: AFRGWGGHJYMSDU-NKGNXCQNSA-N
• SMILES: CC1CC2(C(C1OC(=O)C3=CC=CC=C3)C(C(=C)C(CC4C(C4(C)C)C=C(C2=O)C)OC(=O)C5=CC=CC=C5)OC(=O)C)OC(=O)C

Euphorbia factor L2 (Cat No.:I017698) is a compound derived from the seeds of the Euphorbia lathyris L. plant. This erythrethane diterpene has demonstrated promising anticancer activity by inducing apoptosis through the mitochondrial pathway. Euphorbia factor L2 has also shown strong cytotoxicity against cancer cells. As a natural compound, Euphorbia factor L2 offers potential as a new anticancer agent and may serve as a valuable tool in cancer research.

Reference

[1]. Lin M, et al. Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway. Acta Pharm Sin B. 2017 Jan;7(1):59-64.