EVT-101 free base

• CAT Number: I027168
• CAS Number: 627525-33-1
• Molecular Formula: C16H13F3N4
• Molecular Weight: 318.30
• Purity: 98%
• Synonyms: EVT-101 free base; EVT-101; EVT 101; EVT101; ENS-101; ENS 101; ENS101
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 5-(3-Difluoromethyl-4-fluorophenyl)-3-(2-methylimidazol-1-ylmethyl)pyridazine
• InChI: InChI=1S/C16H13F3N4/c1-10-20-4-5-23(10)9-13-6-12(8-21-22-13)11-2-3-15(17)14(7-11)16(18)19/h2-8,16H,9H2,1H3
• InChIKey: BOVUHBFXPNLTKF-UHFFFAOYSA-N
• SMILES: CC1=NC=CN1CC2=NN=CC(C3=CC=C(F)C(C(F)F)=C3)=C2

EVT-101 Free Base(CAT: I027168) is a highly selective NMDA receptor antagonist, specifically targeting the NR2B subunit. This compound is widely used in neuroscience research to study excitatory neurotransmission, synaptic plasticity, and neurodegenerative diseases. By selectively modulating NR2B-containing NMDA receptors, EVT-101 Free Base offers insights into the mechanisms underlying conditions such as Alzheimer’s disease, depression, and chronic pain. Its exceptional selectivity reduces off-target effects, making it a reliable tool for in vitro and in vivo applications. With high purity and stability, EVT-101 Free Base supports advancements in drug discovery and the development of therapeutics targeting NMDA receptor dysfunction.