For research use only. Not for therapeutic Use.
EVT-401 (P2X7 receptor antagonist-1) is a purinergic P2X7 receptor antagonist. EVT-401 has efficacy of combating neuroinflammation[1].
| Catalog Number | I043859 |
| Synonyms | 2-[3-fluoro-4-(trifluoromethyl)phenyl]-N-[2-(1-hydroxypropan-2-yl)-6-methyl-1-oxoisoquinolin-5-yl]acetamide |
| Molecular Formula | C22H20F4N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H20F4N2O3/c1-12-3-5-16-15(7-8-28(21(16)31)13(2)11-29)20(12)27-19(30)10-14-4-6-17(18(23)9-14)22(24,25)26/h3-9,13,29H,10-11H2,1-2H3,(H,27,30) |
| InChIKey | JECILOFRRYCNDH-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(C=C1)C(=O)N(C=C2)C(C)CO)NC(=O)CC3=CC(=C(C=C3)C(F)(F)F)F |
| Reference | [1]. Binan Zhu, et al. Identification and characterization of related substances in EVT-401 by hyphenated LC-MS techniques. J Pharm Anal |
