Exisulind

• CAT Number: I006751
• CAS Number: 59864-04-9
• Molecular Formula: C20H17FO4S
• Molecular Weight: 372.41
• Purity: ≥95%
• Synonyms: 2-[(3E)-6-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]acetic acid
• InChI: InChI=1S/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9+
• InChIKey: MVGSNCBCUWPVDA-RQZCQDPDSA-N
• SMILES: CC\1=C(C2=C(/C1=C/C3=CC=C(C=C3)S(=O)(=O)C)C=CC(=C2)F)CC(=O)O

Exisulind（Cat No.:I006751）is a small molecule compound that acts as a selective inhibitor of cyclic GMP-specific phosphodiesterase (PDE5), which plays a role in regulating cellular signaling pathways. It has been studied for its potential in cancer treatment, particularly in colon cancer, as it may promote apoptosis (programmed cell death) and inhibit tumor growth. Exisulind also has anti-inflammatory properties and may enhance the effects of other chemotherapeutic agents. Ongoing research is exploring its ability to prevent cancer recurrence and its broader applications in other cancer types, as well as its safety and efficacy profile.