(E/Z)-4,4’-Dihydroxy-N-desmethyl Tamoxifen-d3

• CAT Number: R046750
• CAS Number: 1246832-93-8
• Molecular Formula: C25H27NO3
• Molecular Weight: 392.51
• Purity: ≥95%
• Synonyms: (E/Z)-4’-Hydroxy Endoxifen-d3
• Storage: -20°C
• IUPAC Name: 4-[(Z)-1-(4-hydroxyphenyl)-1-[4-[2-(trideuteriomethylamino)ethoxy]phenyl]but-1-en-2-yl]phenol
• InChI: InChI=1S/C25H27NO3/c1-3-24(18-4-10-21(27)11-5-18)25(19-6-12-22(28)13-7-19)20-8-14-23(15-9-20)29-17-16-26-2/h4-15,26-28H,3,16-17H2,1-2H3/b25-24-/i2D3
• InChIKey: JYBJJTCUEOUMEV-CANUYGMUSA-N
• SMILES: [2H]C([2H])([2H])NCCOC1=CC=C(C=C1)/C(=C(/CC)\C2=CC=C(C=C2)O)/C3=CC=C(C=C3)O

(E/Z)-4,4’-Dihydroxy-N-desmethyl Tamoxifen-d3（Cat No.:R046750） is a deuterated form of the active metabolite of tamoxifen, featuring three deuterium atoms. This isotopic labeling enhances the stability and detection of the metabolite in pharmacokinetic and pharmacodynamic studies, particularly in the context of breast cancer treatment research. It allows researchers to precisely track the metabolism and efficacy of tamoxifen, contributing to a deeper understanding of its therapeutic pathways and resistance mechanisms. (E/Z)-4,4’-Dihydroxy-N-desmethyl Tamoxifen-d3 is essential for advancing breast cancer treatments and improving patient outcomes.