For research use only. Not for therapeutic Use.
EZM 2302 (CAT: I020110) emerges as a potent inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1), displaying remarkable efficacy with an IC50 value of 6 nM. By targeting CARM1, this inhibitor influences the methylation of arginine residues, which is crucial for regulating gene expression and various cellular processes. EZM 2302’s high specificity for CARM1 makes it a promising candidate for disrupting aberrant gene regulation associated with diseases such as cancer.
| Catalog Number | I020110 |
| CAS Number | 1628830-21-6 |
| Molecular Formula | C₂₉H₃₇ClN₆O₅ |
| Purity | ≥95% |
| Target | Histone Methyltransferase |
| Reference | [1]. Drew AE, et al. Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma. Sci Rep. 2017 Dec 21;7(1):17993. |
