For research use only. Not for therapeutic Use.
Ezurpimtrostat (Cat No.: I027193) is an investigational small molecule designed to inhibit the enzyme inosine monophosphate dehydrogenase (IMPDH). By targeting IMPDH, it aims to regulate purine metabolism, which is crucial for the proliferation of rapidly dividing cells, such as cancer cells and those involved in autoimmune disorders. Preclinical studies suggest that Ezurpimtrostat may offer therapeutic benefits in conditions like cancers and certain autoimmune diseases by suppressing abnormal cell growth. Ongoing clinical trials are evaluating its safety, efficacy, and potential in various treatment regimens.
| CAS Number | 1914148-72-3 |
| Synonyms | Ezurpimtrostat |
| Molecular Formula | C25H31ClN4 |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 4-[4-(tert-butylamino)piperidin-1-yl]-N-[(4-chlorophenyl)methyl]quinolin-2-amine |
| InChI | InChI=1S/C25H31ClN4/c1-25(2,3)29-20-12-14-30(15-13-20)23-16-24(28-22-7-5-4-6-21(22)23)27-17-18-8-10-19(26)11-9-18/h4-11,16,20,29H,12-15,17H2,1-3H3,(H,27,28) |
| InChIKey | QVXSJSXAVQJXOV-UHFFFAOYSA-N |
| SMILES | ClC1=CC=C(CNC2=NC3=CC=CC=C3C(N4CCC(NC(C)(C)C)CC4)=C2)C=C1 |
