F-1393 HCl

• CAT Number: I027202
• CAS Number: 56775-92-9
• Molecular Formula: C18H20Cl2N2O4
• Molecular Weight: 399.27
• Purity: 98%
• Synonyms: F 1393 HCl; F1393 HCl; F-1393 HCl; F-1393 hydrochloride
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-(pyridine-3-carbonylamino)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate;hydrochloride
• InChI: InChI=1S/C18H19ClN2O4.ClH/c1-18(2,25-15-7-5-14(19)6-8-15)17(23)24-11-10-21-16(22)13-4-3-9-20-12-13;/h3-9,12H,10-11H2,1-2H3,(H,21,22);1H
• InChIKey: VBQSOVUBXWFWRS-UHFFFAOYSA-N
• SMILES: CC(C)(C(=O)OCCNC(=O)C1=CN=CC=C1)OC2=CC=C(C=C2)Cl.Cl

F-1393 HCl（Cat No.:I027202）is a potent, selective small molecule inhibitor of the enzyme fibroblast activation protein (FAP). FAP is involved in tissue remodeling and is overexpressed in various cancers, including solid tumors. By inhibiting FAP, F-1393 HCl has shown potential in disrupting tumor microenvironment interactions, thereby hindering tumor progression and metastasis. It has been investigated for use in cancer therapies, particularly in combination with other anticancer agents to improve efficacy. Ongoing research focuses on its safety, effectiveness, and potential as part of novel therapeutic strategies for treating cancer and fibrotic diseases.