For research use only. Not for therapeutic Use.
F-1643 HCl(Cat No.:I027212)is a selective and potent inhibitor of the protein kinase CK2 (casein kinase 2), an enzyme that regulates various cellular functions, including cell growth, survival, and proliferation. CK2 is often dysregulated in cancer, making it a potential target for therapeutic intervention. F-1643 HCl has been studied for its ability to inhibit CK2 activity, potentially reducing tumor growth and enhancing the effects of other cancer treatments. Preclinical studies suggest its potential as an anticancer agent, although further research is needed to assess its safety, efficacy, and clinical applications in oncology.
Catalog Number | I027212 |
CAS Number | 68398-01-6 |
Synonyms | F-1643 HCl; F1643 HCl; F 1643 HCl; F-1643 hydrochloride; F1643 hydrochloride; F 1643 hydrochloride |
Molecular Formula | C17H22ClNO3 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | (2-hydroxy-3-methoxyphenyl)methyl-(1-hydroxy-1-phenylpropan-2-yl)azanium;chloride |
InChI | InChI=1S/C17H21NO3.ClH/c1-12(16(19)13-7-4-3-5-8-13)18-11-14-9-6-10-15(21-2)17(14)20;/h3-10,12,16,18-20H,11H2,1-2H3;1H |
InChIKey | WBDFKFGPKWDYAO-UHFFFAOYSA-N |
SMILES | CC(C(C1=CC=CC=C1)O)[NH2+]CC2=C(C(=CC=C2)OC)O.[Cl-] |