FABP-IN-2

• CAT Number: I041768
• CAS Number: 1426533-99-4
• Molecular Formula: C25H21ClN2O3
• Molecular Weight: 432.90
• Purity: ≥95%
• Synonyms: 4-[2-[1-(2-chlorophenyl)-5-phenylpyrazol-3-yl]phenoxy]butanoic acid
• InChI: InChI=1S/C25H21ClN2O3/c26-20-12-5-6-13-22(20)28-23(18-9-2-1-3-10-18)17-21(27-28)19-11-4-7-14-24(19)31-16-8-15-25(29)30/h1-7,9-14,17H,8,15-16H2,(H,29,30)
• InChIKey: DLWPLLKZMMWLHC-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=CC(=NN2C3=CC=CC=C3Cl)C4=CC=CC=C4OCCCC(=O)O

FABP-IN-2 is a novel FABP3 ligand. FABP-IN-2 inhibits FABP3/FABP4 with an IC50 of 1.16 μM and 4.27 μM respectively[1].
FABP-IN-2 (Compound 13p) inhibits FABP3/FABP4 with an IC50 of 1.16 μM and 4.27 μM respectively[1].

Reference

[1]. Beniyama Y, et al. Structure-guided design, synthesis and in vitro evaluation of a series of pyrazole-based fatty acid binding protein (FABP) 3 ligands. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1662-6.
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