FAK-IN-2

• CAT Number: I043886
• CAS Number: 2872588-02-6
• Molecular Formula: C28H31ClN8O3
• Molecular Weight: 563.05
• Purity: ≥95%
• Synonyms: 2-[[5-chloro-2-[4-[4-[(2R)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
• InChI: InChI=1S/C28H31ClN8O3/c1-4-24(38)32-18(2)27(40)37-15-13-36(14-16-37)20-11-9-19(10-12-20)33-28-31-17-22(29)25(35-28)34-23-8-6-5-7-21(23)26(39)30-3/h4-12,17-18H,1,13-16H2,2-3H3,(H,30,39)(H,32,38)(H2,31,33,34,35)/t18-/m1/s1
• InChIKey: SQMGCXJZSMCVHC-GOSISDBHSA-N
• SMILES: C[C@H](C(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4C(=O)NC)Cl)NC(=O)C=C

FAK-IN-2（Cat No.:I043886）is a small molecule inhibitor targeting focal adhesion kinase (FAK), a key regulator of cell adhesion, migration, and survival. FAK plays a crucial role in various cellular processes, including cancer metastasis and tumor progression. By inhibiting FAK, FAK-IN-2 disrupts these processes, potentially limiting the ability of cancer cells to invade surrounding tissues. It is being studied for its therapeutic potential in cancer treatment, particularly in metastatic cancers, as well as in other diseases characterized by abnormal cell signaling.