For research use only. Not for therapeutic Use.
FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].
FAK-IN-7 (0-10 µM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation[1].
| Catalog Number | I042885 |
| CAS Number | 19948-85-7 |
| Synonyms | N-[5-(4-methylphenyl)-1,3,4-thiadiazol-2-yl]benzamide |
| Molecular Formula | C16H13N3OS |
| Purity | ≥95% |
| InChI | InChI=1S/C16H13N3OS/c1-11-7-9-13(10-8-11)15-18-19-16(21-15)17-14(20)12-5-3-2-4-6-12/h2-10H,1H3,(H,17,19,20) |
| InChIKey | SIHYHKOFZPWMHZ-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)C2=NN=C(S2)NC(=O)C3=CC=CC=C3 |
| Reference | [1]. Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95. |
