For research use only, not for therapeutic use.
Famciclovir (INN) is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is also indicated for treatment of recurrent episodes of herpes simplex in HIV patients. It is a prodrug form of penciclovir with improved oral bioavailability.
Catalog Number | A000218 |
CAS Number | 104227-87-4 |
Synonyms | 104227-87-4; Famvir; Famciclovirum; 2-(2-(2-Amino-9H-purin-9-yl)ethyl)propane-1,3-diyl diacetate; BRL-42810 |
Molecular Formula | C14H19N5O4 |
Purity | ≥95% |
Target | HSV |
Solubility | >8.8mg/mL in DMSO |
Storage | -20°C |
InChI | 1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18) |
InChIKey | GGXKWVWZWMLJEH-UHFFFAOYSA-N |
SMILES | CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C |
Reference | 1: Kim SH, Yeo SG. Response to Letter to the Editor: /Comparison of Acyclovir and 2: Patel CV, Kishore K. Concomitant Intravitreal Ganciclovir and Dexamethasone 3: Pridgen WL, Duffy C, Gendreau JF, Gendreau RM. A famciclovir + celecoxib 4: Kim HJ, Jung J, Kim SS, Byun JY, Park MS, Yeo SG. Comparison of Acyclovir and 5: Polansky H, Javaherian A, Itzkovitz E. Clinical study in genital herpes: 6: Thomasy SM, Shull O, Outerbridge CA, Lim CC, Freeman KS, Strom AR, Kass PH, <br> 8: Sebbag L, Thomasy SM, Woodward AP, Knych HK, Maggs DJ. Pharmacokinetic 9: Kim HJ, Kim SH, Jung J, Kim SS, Byun JY, Park MS, Yeo SG. Comparison of 10: Yaldiz M, Solak B, Kara RO, Cosansu N, Erdem MT. Comparison of Famciclovir, |