Famotidine-13C,d4 Amide Impurity

• CAT Number: R048503
• CAS Number: 1327321-45-8
• Molecular Formula: C8H13N5OS2
• Molecular Weight: 264.363
• Purity: ≥95%
• Synonyms: 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide-13C,d4
• Storage: -20°C
• IUPAC Name: 2,2,3,3-tetradeuterio-3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]propanamide
• InChI: InChI=1S/C8H13N5OS2/c9-6(14)1-2-15-3-5-4-16-8(12-5)13-7(10)11/h4H,1-3H2,(H2,9,14)(H4,10,11,12,13)/i1D2,2D2,6+1
• InChIKey: BLXXXPVCYVHTQA-VKKAIXRESA-N
• SMILES: [2H]C([2H])([13C](=O)N)C([2H])([2H])SCC1=CSC(=N1)N=C(N)N

Famotidine-13C,d4 Amide Impurity is a deuterium and carbon-13 labeled analogue of a potential impurity found in famotidine, a histamine H2-receptor antagonist used to treat ulcers and gastroesophageal reflux disease (GERD). This labeled impurity is utilized in pharmaceutical research to ensure the purity and quality of famotidine formulations. By serving as an internal standard in mass spectrometry, it allows for precise quantification and detection of impurities during the drug development and manufacturing processes. Additionally, it aids in the validation of analytical methods, ensuring compliance with regulatory standards and enhancing the reliability of stability and degradation studies.