For research use only. Not for therapeutic Use.
FAP Ligand 1 (FL), a high-affinity FAP small-molecule ligand, is used to target attached drugs to FAP-expressing fibroblasts and can be used in radiation imaging studies of targeted cancers[1].
| Catalog Number | I040900 |
| CAS Number | 2230625-76-8 |
| Synonyms | 2-(aminomethyl)-N-[(2S)-1-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-1-oxopropan-2-yl]pyridine-4-carboxamide |
| Molecular Formula | C15H17F2N5O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H17F2N5O2/c1-9(14(24)22-8-15(16,17)5-12(22)7-19)21-13(23)10-2-3-20-11(4-10)6-18/h2-4,9,12H,5-6,8,18H2,1H3,(H,21,23)/t9-,12-/m0/s1 |
| InChIKey | RWXULCZIWCOLME-CABZTGNLSA-N |
| SMILES | CC(C(=O)N1CC(CC1C#N)(F)F)NC(=O)C2=CC(=NC=C2)CN |
| Reference | [1]. Jyoti Roy, et al. Design and validation of fibroblast activation protein alpha targeted imaging and therapeutic agents.Theranostics 2020; 10(13):5778-5789. |
