For research use only. Not for therapeutic Use.
FAP Ligand 1 (CAT: I040900) is a high-affinity small-molecule ligand designed to target fibroblast activation protein (FAP)-expressing fibroblasts. By binding specifically to FAP, FL enables the targeted delivery of therapeutic agents or imaging probes to tumor-associated fibroblasts in cancer tissues. This ligand can be used in radiation imaging studies to enhance the visualization of FAP-expressing cells, aiding in the detection and monitoring of cancers that have a significant stromal component. FAP Ligand 1 holds promise for use in cancer imaging, particularly in targeted cancer therapies and diagnostic research, making it highly relevant for Cancer Disease Research.
| CAS Number | 2230625-76-8 |
| Synonyms | 2-(aminomethyl)-N-[(2S)-1-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-1-oxopropan-2-yl]pyridine-4-carboxamide |
| Molecular Formula | C15H17F2N5O2 |
| Purity | ≥95% |
| IUPAC Name | 2-(aminomethyl)-N-[(2S)-1-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-1-oxopropan-2-yl]pyridine-4-carboxamide |
| InChI | InChI=1S/C15H17F2N5O2/c1-9(14(24)22-8-15(16,17)5-12(22)7-19)21-13(23)10-2-3-20-11(4-10)6-18/h2-4,9,12H,5-6,8,18H2,1H3,(H,21,23)/t9-,12-/m0/s1 |
| InChIKey | RWXULCZIWCOLME-CABZTGNLSA-N |
| SMILES | C[C@@H](C(=O)N1CC(C[C@H]1C#N)(F)F)NC(=O)C2=CC(=NC=C2)CN |
