For research use only. Not for therapeutic Use.
Farnesyl pyrophosphate is an intermediate in the HMG-<wbr></wbr>CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-<wbr></wbr>translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors (IC<sub>50</sub> = 45 μM), attenuating platelet aggregation. It has also been shown to regulate adipocyte function as an endogenous PPARγ agonist. Additionally, because of a flexible hydrocarbon chain that enables different conformations, FPP is a promiscuous ligand for a subset of nuclear receptors.
| Catalog Number | R046694 |
| CAS Number | 116057-57-9 |
| Synonyms | Diphosphoric Acid P-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] Ester Ammonium Salt; (E,E)-Diphosphoric Acid Mono(3,7,11-trimethyl-2,6,10-dodecatrienyl) Ester Triammonium Salt; |
| Molecular Formula | C15H25O7P2 • 3NH4 |
| Purity | ≥95% |
| Storage | -20°C |
| InChIKey | GSWRJNPTNZUHOV-VLCVYXDNSA-N |
