FASN-IN-5

• CAT Number: I043853
• CAS Number: 1309805-49-9
• Molecular Formula: C29H26N4O2
• Molecular Weight: 462.54
• Purity: ≥95%
• Synonyms: [(3S)-3-[[2-[4-(1-benzofuran-5-yl)phenyl]imidazo[4,5-c]pyridin-1-yl]methyl]pyrrolidin-1-yl]-cyclopropylmethanone
• InChI: InChI=1S/C29H26N4O2/c34-29(22-5-6-22)32-13-10-19(17-32)18-33-26-9-12-30-16-25(26)31-28(33)21-3-1-20(2-4-21)23-7-8-27-24(15-23)11-14-35-27/h1-4,7-9,11-12,14-16,19,22H,5-6,10,13,17-18H2/t19-/m1/s1
• InChIKey: MXQGGBTXHJSPPG-LJQANCHMSA-N
• SMILES: C1CN(C[C@@H]1CN2C3=C(C=NC=C3)N=C2C4=CC=C(C=C4)C5=CC6=C(C=C5)OC=C6)C(=O)C7CC7

FASN-IN-5（Cat No.:I043853）is a small molecule inhibitor of fatty acid synthase (FASN), an enzyme responsible for the de novo synthesis of fatty acids, which is crucial for tumor growth and survival. By inhibiting FASN, FASN-IN-5 disrupts lipid metabolism and reduces the availability of essential fatty acids required for cellular processes like membrane synthesis and energy storage. It is being explored for its potential as a cancer therapeutic, as many cancers, particularly breast and prostate cancers, exhibit upregulated FASN activity. Research is ongoing to evaluate its effectiveness in suppressing tumor growth and its broader therapeutic applications.