FASORACETAM

• CAT Number: M010728
• CAS Number: 110958-19-5
• Molecular Formula: C10H16N2O2
• Molecular Weight: 196.25
• Purity: ≥95%
• Synonyms: N-(5-Oxo-D-prolyl)piperidine; NS 105 (pharmaceutical)
• Storage: -20°C
• IUPAC Name: (5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one
• InChI: InChI=1S/C10H16N2O2/c13-9-5-4-8(11-9)10(14)12-6-2-1-3-7-12/h8H,1-7H2,(H,11,13)/t8-/m1/s1
• InChIKey: GOWRRBABHQUJMX-MRVPVSSYSA-N
• SMILES: C1CCN(CC1)C(=O)C2CCC(=O)N2

Fasoracetam (CAS 110958-19-5), also known as NS-105; NFC-1; LAM-105, is a GABA receptor modulator potentially for the treatment of attention deficit hyperactivity disorder. It is a nootropic, and has been in a clinical trial for attention deficit hyperactivity disorder. In in vitro studies on mouse neurons, fasoracetam modulated mGluR II/III activity. In studies in rats, it blocked memory disruptions caused by baclofen, a GABAB agonist and upregulated production of GABAB receptors after repeat dosing.

Reference

1:Drugs R D. 1999 Aug;2(2):135-6. Fasoracetam. LAM 105, NS 105. PMID: 10820660