Fce 22250

For research use only. Not for therapeutic Use.

  • CAT Number: I027325
  • CAS Number: 84475-07-0
  • Molecular Formula: C44H58N4O12
  • Molecular Weight: 834.96
  • Purity: 98%
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FCE 22250(Cat No.:I027325)is a selective serotonin (5-HT) receptor antagonist, primarily targeting the 5-HT3 receptor subtype. It has been investigated for its potential therapeutic applications in treating conditions associated with excessive serotonin activity, such as nausea, vomiting, and certain gastrointestinal disorders. The 5-HT3 receptor is involved in the regulation of gastrointestinal motility and emesis. FCE 22250 works by blocking these receptors, which may reduce symptoms like nausea, often induced by chemotherapy or other treatments. Research into its efficacy and safety is ongoing, with potential applications in both gastrointestinal and neuropsychiatric disorders.


Catalog Number I027325
CAS Number 84475-07-0
Synonyms

Fce 22250; Fce-22250; Fce22250

Molecular Formula C44H58N4O12
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21E)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-26-[(Z)-[(E)-piperidin-1-ylmethylidenehydrazinylidene]methyl]-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate
InChI InChI=1S/C44H58N4O12/c1-22-14-13-15-23(2)43(56)47-34-29(20-45-46-21-48-17-11-10-12-18-48)38(53)31-32(39(34)54)37(52)27(6)41-33(31)42(55)44(8,60-41)58-19-16-30(57-9)24(3)40(59-28(7)49)26(5)36(51)25(4)35(22)50/h13-16,19-22,24-26,30,35-36,40,50-54H,10-12,17-18H2,1-9H3,(H,47,56)/b14-13+,19-16+,23-15+,45-20-,46-21+/t22-,24+,25+,26+,30-,35-,36+,40+,44-/m0/s1
InChIKey JEGGQYICWGMXOZ-FZMNFFEUSA-N
SMILES C[C@H]1/C=C/C=C(/C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C=N\N=C\N5CCCCC5)\C

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