For research use only. Not for therapeutic Use.
FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.
| Catalog Number | I027331 |
| CAS Number | 113869-44-6 |
| Synonyms | FCE-24379; FCE24379; FCE 24379 |
| Molecular Formula | C20H22N4O2 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2,4(1H,3H)-Pyrimidinedione, dihydro-1-((2,7,8,9,9a,10-hexahydro-9-methylpyrrolo(3',2':5,6)cyclohept(1,2,3-cd)indol-7-yl)methyl)-, (7R-cis)- |
| InChI | InChI=1S/C20H22N4O2/c1-23-10-14(11-24-6-5-18(25)22-20(24)26)15-7-12-3-2-4-16-19(12)13(9-21-16)8-17(15)23/h2-4,7,9,14,17,21H,5-6,8,10-11H2,1H3,(H,22,25,26)/t14-,17-/m1/s1 |
| InChIKey | OJPZLSMBNYRZIW-RHSMWYFYSA-N |
| SMILES | CN1C[C@H](CN2CCC(=O)NC2=O)C3=Cc4cccc5[nH]cc(C[C@@H]13)c45 |
| Reference | 1. Salvati P, Vaghi F, Colombo M, Bianchi G. A new selective antagonist of vascular serotonin receptors lowers blood pressure in spontaneously hypertensive rats. Drugs. 1988;36 Suppl 1:105-9. doi: 10.2165/00003495-198800361-00019. PMID: 3240722. |
