FD-IN-1

• CAT Number: I018998
• CAS Number: 1646682-14-5
• Molecular Formula: C₂₃H₂₃NO₄
• Molecular Weight: 377.43
• Purity: ≥95%
• Target: Complement System
• IUPAC Name: 2-[2-[[3-[3-[(1S)-1-amino-2-hydroxyethyl]phenyl]phenyl]methoxy]phenyl]acetic acid
• InChI: InChI=1S/C23H23NO4/c24-21(14-25)19-9-4-8-18(12-19)17-7-3-5-16(11-17)15-28-22-10-2-1-6-20(22)13-23(26)27/h1-12,21,25H,13-15,24H2,(H,26,27)/t21-/m1/s1
• InChIKey: XHLXBWRISOPXQB-OAQYLSRUSA-N
• SMILES: C1=CC=C(C(=C1)CC(=O)O)OCC2=CC(=CC=C2)C3=CC(=CC=C3)[C@@H](CO)N

FD-IN-1 (Cat.No:I018998) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Inquire FD-IN-1 online by filling out the inquiry form, we will get back to you within 24 hours!

Reference

[1]. Karki RG, et al. Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway. J Med Chem. 2019 May 9;62(9):4656-4668.