For research use only. Not for therapeutic Use.
FDW028(CAT: I040689) is a small-molecule inhibitor designed to selectively target the PD-1/PD-L1 immune checkpoint pathway, a critical regulator in cancer immunotherapy. By disrupting the interaction between PD-1 and PD-L1, FDW028 enhances T-cell activation and restores immune surveillance against tumor cells. It is a valuable research tool for studying tumor immunology, immune evasion mechanisms, and the development of next-generation immuno-oncology therapies. FDW028 demonstrates strong binding affinity, favorable pharmacokinetics, and efficacy in preclinical models. Ideal for cancer research and drug discovery, this compound supports the exploration of novel strategies to potentiate immune responses in a variety of malignancies.
| CAS Number | 2768426-49-7 |
| Synonyms | 5-[(benzylamino)methyl]-2-[(4-ethylphenyl)methylamino]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one |
| Molecular Formula | C22H24N6O |
| Purity | ≥95% |
| IUPAC Name | 5-[(benzylamino)methyl]-2-[(4-ethylphenyl)methylamino]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one |
| InChI | InChI=1S/C22H24N6O/c1-2-16-8-10-18(11-9-16)14-24-21-26-22-25-19(12-20(29)28(22)27-21)15-23-13-17-6-4-3-5-7-17/h3-12,23H,2,13-15H2,1H3,(H2,24,25,26,27) |
| InChIKey | PAWBAUIXKSTNNX-UHFFFAOYSA-N |
| SMILES | CCC1=CC=C(C=C1)CNC2=NC3=NC(=CC(=O)N3N2)CNCC4=CC=CC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
