Febuxostat impurity 7

• CAT Number: I014937
• CAS Number: 1350352-70-3
• Molecular Formula: C16H18N2O4S
• Molecular Weight: 334.39
• Purity: ≥95%
• Synonyms: 2-[3-[(E)-hydroxyiminomethyl]-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
• InChI: InChI=1S/C16H18N2O4S/c1-9(2)8-22-13-5-4-11(6-12(13)7-17-21)15-18-10(3)14(23-15)16(19)20/h4-7,9,21H,8H2,1-3H3,(H,19,20)/b17-7+
• InChIKey: MDMGIABSBHFMNF-REZTVBANSA-N
• SMILES: CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C=NO)C(=O)O

Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

Reference

[1]. Manne Satyanarayana Reddy, et al. Process for preparation of 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid and its pharmaceutically acceptable salts. WO2011141933A2.