Felodipine

• CAT Number: A001024
• CAS Number: 72509-76-3
• Molecular Formula: C18H19Cl2NO4
• Molecular Weight: 384.25
• Purity: ≥95%
• Synonyms: 72509-76-3; Plendil; Flodil; Munobal; Renedil
• Target: Neuronal Signaling
• Solubility: >17.7mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: 5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• InChI: 1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
• InChIKey: RZTAMFZIAATZDJ-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C

Felodipine (CAS 72509-76-3) is a calcium channel blocker (calcium antagonist), used to control hypertension. Felodipine prevents calcium from being released within the muscle cells of the small arteries and thereby causes the muscles to relax and the arteries to dilate or expand. Dilation of arteries reduces blood pressure. Felodipine has little or no effect on the muscles of veins or the heart. Felodipine was approved by the FDA in 1991.