For research use only. Not for therapeutic Use.
FEMA4774, also known as S9632, is the novel T1R2/T1R3 positive allosteric modulator. FEMA4774 shows obvious enhancement of the sweetness of sucrose in sensory evaluation tests.
| Catalog Number | I027367 |
| CAS Number | 1359963-68-0 |
| Synonyms | FEMA4774; FEMA-4774; FEMA 4774; S9632; S-9632; S 9632; |
| Molecular Formula | C19H25N3O4 |
| Purity | 98% |
| Target | Taste Receptor |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 4-amino-5-(3-(isopropylamino)-2,2-dimethyl-3-oxopropoxy)-2-methylquinoline-3-carboxylic acid |
| InChI | InChI=1S/C19H25N3O4/c1-10(2)21-18(25)19(4,5)9-26-13-8-6-7-12-15(13)16(20)14(17(23)24)11(3)22-12/h6-8,10H,9H2,1-5H3,(H2,20,22)(H,21,25)(H,23,24) |
| InChIKey | RHXLOOCFQPJWBW-UHFFFAOYSA-N |
| SMILES | O=C(C1=C(N)C2=C(OCC(C)(C)C(NC(C)C)=O)C=CC=C2N=C1C)O |
| Reference | 1: Arthur AJ, Karanewsky DS, Liu H, Chi B, Markison S. Toxicological evaluation |
