Femoxetine hydrochloride

• CAT Number: I027370
• CAS Number: 56222-04-9
• Molecular Formula: C20H26ClNO2
• Molecular Weight: 347.88
• Purity: 98%
• Synonyms: Femoxetine hydrochloride; Femoxetine HCl; FG4963; FG-4963; FG 4963; Malexil
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (3R,4S)-3-[(4-methoxyphenoxy)methyl]-1-methyl-4-phenylpiperidine;hydrochloride
• InChI: InChI=1S/C20H25NO2.ClH/c1-21-13-12-20(16-6-4-3-5-7-16)17(14-21)15-23-19-10-8-18(22-2)9-11-19;/h3-11,17,20H,12-15H2,1-2H3;1H/t17-,20-;/m1./s1
• InChIKey: ORJNLCKHRRUOMU-OGPPPPIKSA-N
• SMILES: CN1CC[C@@H]([C@H](C1)COC2=CC=C(C=C2)OC)C3=CC=CC=C3.Cl

Femoxetine Hydrochloride(CAT: I027370) is a selective serotonin reuptake inhibitor (SSRI) primarily used in neuropharmacology and psychiatry research. By inhibiting the reuptake of serotonin (5-HT) into presynaptic neurons, it increases serotonin levels in the synaptic cleft, enhancing serotonergic neurotransmission. This mechanism makes Femoxetine Hydrochloride a valuable tool for studying mood disorders such as depression and anxiety. It supports investigations into serotonin’s role in emotional regulation, neuroplasticity, and the development of novel antidepressants. Researchers also use it to explore SSRI pharmacodynamics, side effects, and its therapeutic potential in other serotonin-related conditions.