FEN1-IN-3

• CAT Number: I015189
• CAS Number: 2109805-87-8
• Molecular Formula: C₁₅H₁₂N₂O₄
• Molecular Weight: 284.27
• Purity: ≥95%
• Target: FLAP
• Storage: -20°C
• IUPAC Name: 3-hydroxy-1-(4-methoxyphenyl)quinazoline-2,4-dione
• InChI: InChI=1S/C15H12N2O4/c1-21-11-8-6-10(7-9-11)16-13-5-3-2-4-12(13)14(18)17(20)15(16)19/h2-9,20H,1H3
• InChIKey: BBJIIPZSHQTBLW-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)N2C3=CC=CC=C3C(=O)N(C2=O)O

EN1-IN-3 (Cat No.:I015189) is a human flap endonuclease-1 (hFEN1) inhibitor. FEN1-IN-3 stabilizes hFEN1 with an EC50 of 6.8 μM. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Jack C Exell, et al. Cellularly Active N-hydroxyurea FEN1 Inhibitors Block Substrate Entry to the Active Site. Nat Chem Biol. 2016 Oct;12(10):815-21.