Fenoverine

• CAT Number: C000661
• CAS Number: 37561-27-6
• Molecular Formula: C₂₆H₂₅N₃O₃S
• Molecular Weight: 459.56
• Purity: ≥95%
• Synonyms: 2-[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(10H-phenothiazin-10-yl)ethanone; 10-[[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]acetyl]-10H-phenothiazine; Spasmopriv
• Target: Neuronal Signaling
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Appearance: Off-White to Beige Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone
• InChI: InChI=1S/C26H25N3O3S/c30-26(29-20-5-1-3-7-24(20)33-25-8-4-2-6-21(25)29)17-28-13-11-27(12-14-28)16-19-9-10-22-23(15-19)32-18-31-22/h1-10,15H,11-14,16-18H2
• InChIKey: UBAJTZKNDCEGKL-UHFFFAOYSA-N
• SMILES: C1CN(CCN1CC2=CC3=C(C=C2)OCO3)CC(=O)N4C5=CC=CC=C5SC6=CC=CC=C64

Fenoverine (Cat No.:C000661) is a medication with antispasmodic and smooth muscle relaxant properties, primarily used to alleviate gastrointestinal and genitourinary tract spasms. It may be employed to treat conditions such as irritable bowel syndrome and dysmenorrhea. Fenoverine is thought to work by modulating calcium ion influx into smooth muscle cells, reducing contractions, and relieving pain associated with muscle spasms.

Reference

Diddi, S., et al.: Int. J. Pharm. Pharm. Sci., 6, 227-231 (2014); Deodhar, P., et al.: J. Pharm. Res., 5, 3406-3409 (2012); Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009), Baell, J., et al.: J. Med. Chem., 53, 2719 (2010), Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010), Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010), Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010);