For research use only. Not for therapeutic Use.
Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells[1][2][3].
| Catalog Number | R047536 |
| CAS Number | 67564-91-4 |
| Synonyms | (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine |
| Molecular Formula | C20H33NO |
| Purity | ≥95% |
| InChI | InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ |
| InChIKey | RYAUSSKQMZRMAI-ALOPSCKCSA-N |
| SMILES | CC1CN(CC(O1)C)CC(C)CC2=CC=C(C=C2)C(C)(C)C |
| Reference | [1]. Costet MF, et al. Ecdysteroid biosynthesis and embryonic development are disturbed in insects (Locusta migratoria) reared on plant diet (Triticum sativum) with a selectively modified sterol profile. Proc Natl Acad Sci U S A. 1987;84(3):643-647. [2]. Marcireau C, et al. In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property. Antimicrob Agents Chemother. 1990;34(6):989-993. [3]. Corio-Costet MF, et al. Inhibition by the fungicide fenpropimorph of cholesterol biosynthesis in 3T3 fibroblasts. Biochem J. 1988;256(3):829-834. |
