For research use only. Not for therapeutic Use.
Fepradinol（Cat No.:I006362）is a synthetic compound that acts as a selective dopamine reuptake inhibitor and has been studied for its potential neuropsychopharmacological effects. It is thought to enhance dopamine neurotransmission by inhibiting the reuptake of dopamine in the brain, which may lead to improved mood, cognition, and motor function. Fepradinol has been investigated as a potential treatment for conditions like depression and Parkinson’s disease, due to its dopaminergic activity. However, it is not widely used in clinical practice, and further research is necessary to fully evaluate its safety, efficacy, and potential therapeutic applications.
| Catalog Number | I006362 |
| CAS Number | 63075-47-8 |
| Synonyms | Fepradinol; Dalgen; Flexidol; EL-508; EL 508; EL508;2-((2-hydroxy-2-phenylethyl)amino)-2-methylpropan-1-ol |
| Molecular Formula | C12H19NO2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term or -20 °C for long term |
| IUPAC Name | 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol |
| InChI | InChI=1S/C12H19NO2/c1-12(2,9-14)13-8-11(15)10-6-4-3-5-7-10/h3-7,11,13-15H,8-9H2,1-2H3 |
| InChIKey | PVOOBRUZWPQOER-UHFFFAOYSA-N |
| SMILES | CC(C)(CO)NCC(C1=CC=CC=C1)O |
| Reference | </br>1:Vascular-occlusive contact dermatitis from fepradinol. Santos-Briz A, Antúnez P, Muñoz E, Morán M, Fernández E, Unamuno P.Contact Dermatitis. 2004 Jan;50(1):44-6. No abstract available. PMID: 15059106 </br>2:Photoallergic contact dermatitis from fepradinol. Rodríguez Granados T, Piñeiro G, de la Torre C, Cruces Prado MJ.Contact Dermatitis. 1998 Oct;39(4):194-5. No abstract available. PMID: 9817228 </br>3:No evidence of cross-reaction between fepradinol and other phenylethanolamines. Goday JJ, Yanguas I, González-Güemes M, Oleaga JM, Ilardia R, Soloeta R.Contact Dermatitis. 1997 Mar;36(3):170-1. No abstract available. PMID: 9145277 </br>4:Effects of fepradinol on rat acute models of vascular permeability and leucocyte migration. Masso JM, Villar AM, Conde JR, Martorell J.Agents Actions. 1994 Oct;42(3-4):118-22. PMID: 7879696 </br>5:Allergic contact dermatitis from fepradinol: report of 4 cases and review of the literature. Ortiz-Frutos FJ, Hergueta JP, Quintana I, Zarco C, Iglesias L.Contact Dermatitis. 1994 Sep;31(3):193-5. Review. No abstract available. PMID: 7821022 </br>6:Allergic contact dermatitis from fepradinol. Aranzabal A, De Barrio M, Rodriguez V, Baeza ML, Tornero P.Contact Dermatitis. 1994 Aug;31(2):121. No abstract available. PMID: 7750256 </br>7:Fepradinol allergy: possibly a case of unnoticed cross-reaction due to misclassification. Schnuch A.Contact Dermatitis. 1994 Apr;30(4):243-5. No abstract available. PMID: 8033556 </br>8:Allergic contact dermatitis from fepradinol in a child. Gomez A, Martorell A, de la Cuadra J.Contact Dermatitis. 1994 Jan;30(1):44. No abstract available. PMID: 8156765 </br>9:Mechanism of anti-inflammatory action of fepradinol. Massó JM, Villar AM, Conde JR, Martorell J.Arzneimittelforschung. 1994 Jan;44(1):68-74. PMID: 7907874 </br>10:Effect of fepradinol on rat hind paw oedema induced by several inflammatory agents. Masso JM, Conde JR, Villar AM, Martorell J.J Pharm Pharmacol. 1993 Nov;45(11):959-62. PMID: 7511161 |
