For research use only. Not for therapeutic Use.
Fepradinol, also known as Dalgen and EL-508, is a non-steroidal anti-inflammatory agent used to treat inflammation and pain.
| Catalog Number | I006362 |
| CAS Number | 63075-47-8 |
| Synonyms | Fepradinol; Dalgen; Flexidol; EL-508; EL 508; EL508;2-((2-hydroxy-2-phenylethyl)amino)-2-methylpropan-1-ol |
| Molecular Formula | C12H19NO2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term or -20 °C for long term |
| IUPAC Name | 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol |
| InChI | InChI=1S/C12H19NO2/c1-12(2,9-14)13-8-11(15)10-6-4-3-5-7-10/h3-7,11,13-15H,8-9H2,1-2H3 |
| InChIKey | PVOOBRUZWPQOER-UHFFFAOYSA-N |
| SMILES | CC(C)(CO)NCC(C1=CC=CC=C1)O |
| Reference | </br>1:Vascular-occlusive contact dermatitis from fepradinol. Santos-Briz A, Antúnez P, Muñoz E, Morán M, Fernández E, Unamuno P.Contact Dermatitis. 2004 Jan;50(1):44-6. No abstract available. PMID: 15059106 </br>2:Photoallergic contact dermatitis from fepradinol. Rodríguez Granados T, Piñeiro G, de la Torre C, Cruces Prado MJ.Contact Dermatitis. 1998 Oct;39(4):194-5. No abstract available. PMID: 9817228 </br>3:No evidence of cross-reaction between fepradinol and other phenylethanolamines. Goday JJ, Yanguas I, González-Güemes M, Oleaga JM, Ilardia R, Soloeta R.Contact Dermatitis. 1997 Mar;36(3):170-1. No abstract available. PMID: 9145277 </br>4:Effects of fepradinol on rat acute models of vascular permeability and leucocyte migration. Masso JM, Villar AM, Conde JR, Martorell J.Agents Actions. 1994 Oct;42(3-4):118-22. PMID: 7879696 </br>5:Allergic contact dermatitis from fepradinol: report of 4 cases and review of the literature. Ortiz-Frutos FJ, Hergueta JP, Quintana I, Zarco C, Iglesias L.Contact Dermatitis. 1994 Sep;31(3):193-5. Review. No abstract available. PMID: 7821022 </br>6:Allergic contact dermatitis from fepradinol. Aranzabal A, De Barrio M, Rodriguez V, Baeza ML, Tornero P.Contact Dermatitis. 1994 Aug;31(2):121. No abstract available. PMID: 7750256 </br>7:Fepradinol allergy: possibly a case of unnoticed cross-reaction due to misclassification. Schnuch A.Contact Dermatitis. 1994 Apr;30(4):243-5. No abstract available. PMID: 8033556 </br>8:Allergic contact dermatitis from fepradinol in a child. Gomez A, Martorell A, de la Cuadra J.Contact Dermatitis. 1994 Jan;30(1):44. No abstract available. PMID: 8156765 </br>9:Mechanism of anti-inflammatory action of fepradinol. Massó JM, Villar AM, Conde JR, Martorell J.Arzneimittelforschung. 1994 Jan;44(1):68-74. PMID: 7907874 </br>10:Effect of fepradinol on rat hind paw oedema induced by several inflammatory agents. Masso JM, Conde JR, Villar AM, Martorell J.J Pharm Pharmacol. 1993 Nov;45(11):959-62. PMID: 7511161 |
