Ferulic acid 4-O-sulfate

• CAT Number: I042762
• CAS Number: 86321-29-1
• Molecular Formula: C10H10O7S
• Molecular Weight: 274.25
• Purity: ≥95%
• Synonyms: (E)-3-(3-methoxy-4-sulfooxyphenyl)prop-2-enoic acid
• InChI: InChI=1S/C10H10O7S/c1-16-9-6-7(3-5-10(11)12)2-4-8(9)17-18(13,14)15/h2-6H,1H3,(H,11,12)(H,13,14,15)/b5-3+
• InChIKey: PZPATWACAAOHTJ-HWKANZROSA-N
• SMILES: COC1=C(C=CC(=C1)C=CC(=O)O)OS(=O)(=O)O

Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice[1].
Ferulic acid 4-O-sulfate (0.1-30 μM) causes significant concentration-dependent relaxations in mouse aorta, femoral and saphenous arteries[1].
Ferulic acid 4-O-sulfate (16.13 and 161.3 µg/kg; i.v.; once) relaxes arteries and lowers blood pressure in mice[1].

Reference

[1]. Van Rymenant E, et al. Ferulic acid-4-O-sulfate rather than ferulic acid relaxes arteries and lowers blood pressure in mice. J Nutr Biochem. 2017 Jun;44:44-51.
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