For research use only. Not for therapeutic Use.
FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage[1]. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process[2].
FeTPPS acts as an effective pro-oxidant towards appreciable substrates in vitro in the presence of oxidant. FeTPPS protects cells against oxidative damage induced by H2O2, generated by Glucose (G)-glucose oxidase (GO) system[2].
| Catalog Number | R026172 |
| CAS Number | 90384-82-0 |
| Molecular Formula | C44H28ClFeN4O12S4 |
| Purity | ≥95% |
| Reference | [1]. Giuseppe Bruschetta, et al. FeTPPS Reduces Secondary Damage and Improves Neurobehavioral Functions after Traumatic Brain Injury.Front Neurosci. 2017 Feb 7;11:6. [2]. Pengfei Zhang, et al. Study on the detoxification mechanisms to 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrinato iron(III) chloride (FeTPPS), an efficient pro-oxidant of heme water-soluble analogue. J Inorg Biochem. 2018 Dec;189:40-52. |
