FF-10502

• CAT Number: I027439
• CAS Number: 184302-49-6
• Molecular Formula: C9H12FN3O3S
• Molecular Weight: 261.27
• Purity: 98%
• Synonyms: FF-10502; FF 10502; FF10502; FF-10502-01; FF 10502-01; FF10502-01; FF-1050201; FF 1050201; FF1050201
• Target: Nucleoside Antimetabolite/Analog
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4-amino-1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidin-2-one
• InChI: InChI=1S/C9H12FN3O3S/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6+,7-,8-/m1/s1
• InChIKey: NIDPJRZOVFIBQB-PXBUCIJWSA-N
• SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](S2)CO)O)F

FF-10502(CAT: I027439) is an orally active antimetabolite with a unique mechanism of action targeting tumor cell proliferation. It enters the nucleus and inhibits DNA polymerases, thereby disrupting DNA synthesis and effectively halting cancer cell division. Notably, FF-10502 demonstrates significant anticancer activity by acting on dormant cells, a challenging subset of tumor cells often resistant to conventional therapies. This novel approach makes it a valuable tool for oncology research, particularly in exploring therapeutic strategies for overcoming resistance and eradicating residual tumor cell populations.