FG 7142

• CAT Number: I010236
• CAS Number: 78538-74-6
• Molecular Formula: C13H11N3O
• Molecular Weight: 225.251
• Purity: ≥95%
• Synonyms: N-Methyl-β-carboline-3-carboxamide
• Target: GABA Receptor
• Solubility: Soluble to 75 mM in 1eq. HCl and to 100 mM in DMSO
• Storage: Store at RT
• IUPAC Name: N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide
• InChI: InChI=1S/C13H11N3O/c1-14-13(17)11-6-9-8-4-2-3-5-10(8)16-12(9)7-15-11/h2-7,16H,1H3,(H,14,17)
• InChIKey: QMCOPDWHWYSJSA-UHFFFAOYSA-N
• SMILES: CNC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2

FG 7142(CAT: I010236) is a compound that acts as an inverse agonist and anxiogenic agent. It has been shown to increase tyrosine hydroxylation and cause the upregulation of β-adrenoceptors in the mouse cerebral cortex. FG 7142 exhibits anxiogenic effects, meaning it promotes anxiety-like behaviors in experimental models. It acts by antagonizing or inhibiting the activity of the receptors involved in the regulation of anxiety and stress responses.