FH1

• CAT Number: I000035
• CAS Number: 2719-05-3
• Molecular Formula: C17H18N2O2
• Molecular Weight: 282.3
• Purity: ≥95%
• Synonyms: FH1;Methylenebis-4,4/’-acetanilide;NSC 12407
• Solubility: DMSO: ≥ 13 mg/mL
• Storage: -20°C
• InChIKey: OEXMNSOPAKOPEF-UHFFFAOYSA-N

FH1(BRDK4477) is a small molecule that can enhance the functions of cultured hepatocytes.IC50 value:Target:In vitro: FH1(BRD-K4477) enhances hepatocyte functions, and promotes the maturation of well-differentiated cultures of iHeps, which potentially alleviates a major obstacle to the use of iPS cells as a renewable source of functional human hepatocytes.

Reference

[1]. Shan J, et al. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat Chem Biol. 2013 Aug;9(8):514-20.