FH535-N

• CAT Number: I027465
• Molecular Formula: C16H10Cl2N2O4S
• Molecular Weight: 397.23
• Purity: 98%
• Synonyms: FH535-N; FH535 N; FH535N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2,5-Dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide
• InChI: InChI=1S/C16H10Cl2N2O4S/c17-10-5-6-13(18)16(9-10)25(23,24)19-14-7-8-15(20(21)22)12-4-2-1-3-11(12)14/h1-9,19H
• InChIKey: VZBUNQNZGCGVOO-UHFFFAOYSA-N
• SMILES: O=S(C1=CC(Cl)=CC=C1Cl)(NC2=C3C=CC=CC3=C([N+]([O-])=O)C=C2)=O

FH535-N(CAT: I027465) is a derivative of FH535, known as a dual inhibitor of Wnt/β-catenin and PPAR (peroxisome proliferator-activated receptor) signaling pathways. It is widely utilized in oncology and stem cell research to investigate the regulation of cell proliferation, differentiation, and tumor progression. By disrupting these critical signaling pathways, FH535-N provides insights into cancer biology, including the mechanisms of tumor growth and metastasis, as well as stem cell renewal and differentiation. Its specificity makes FH535-N a valuable tool for preclinical studies focused on developing targeted therapies for Wnt/β-catenin-related diseases, including various cancers and degenerative conditions.