For research use only. Not for therapeutic Use.
FH535-N is a novel inhibitor of the wnt/β-catenin transcriptional activity, demonstrating significant increased rate of apoptosis in huh7 and plc/prf
| Catalog Number | I027465 |
| Synonyms | FH535-N; FH535 N; FH535N |
| Molecular Formula | C16H10Cl2N2O4S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2,5-Dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide |
| InChI | InChI=1S/C16H10Cl2N2O4S/c17-10-5-6-13(18)16(9-10)25(23,24)19-14-7-8-15(20(21)22)12-4-2-1-3-11(12)14/h1-9,19H |
| InChIKey | VZBUNQNZGCGVOO-UHFFFAOYSA-N |
| SMILES | O=S(C1=CC(Cl)=CC=C1Cl)(NC2=C3C=CC=CC3=C([N+]([O-])=O)C=C2)=O |
| Reference | 1: Turcios L, Chacon E, Garcia C, Eman P, Cornea V, Jiang J, Spear B, Liu C, Watt DS, Marti F, Gedaly R. Autophagic flux modulation by Wnt/β-catenin pathway inhibition in hepatocellular carcinoma. PLoS One. 2019 Feb 22;14(2):e0212538. doi: 10.1371/journal.pone.0212538. eCollection 2019. PubMed PMID: 30794613; PubMed Central PMCID: PMC6386480. |
