For research use only. Not for therapeutic Use.
FHT-1205 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 67)[1].
| Catalog Number | I044027 |
| CAS Number | 2368903-18-6 |
| Synonyms | N-[(2S)-4-methylsulfanyl-1-oxo-1-[[4-(3-pyridin-4-ylphenyl)-1,3-thiazol-2-yl]amino]butan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide |
| Molecular Formula | C25H25N5O4S3 |
| Purity | ≥95% |
| InChI | InChI=1S/C25H25N5O4S3/c1-35-13-9-21(27-23(31)20-8-12-30(15-20)37(2,33)34)24(32)29-25-28-22(16-36-25)19-5-3-4-18(14-19)17-6-10-26-11-7-17/h3-8,10-12,14-16,21H,9,13H2,1-2H3,(H,27,31)(H,28,29,32)/t21-/m0/s1 |
| InChIKey | FAYSHZVDWADZMD-NRFANRHFSA-N |
| SMILES | CSCCC(C(=O)NC1=NC(=CS1)C2=CC=CC(=C2)C3=CC=NC=C3)NC(=O)C4=CN(C=C4)S(=O)(=O)C |
| Reference | [1]. Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1. |
