For research use only. Not for therapeutic Use.
FHT-1204 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 70)[1].
| Catalog Number | I044026 |
| CAS Number | 2468048-24-8 |
| Synonyms | N-[(2S)-3-methoxy-1-oxo-1-[[4-(3-pyridin-4-ylphenyl)-1,3-thiazol-2-yl]amino]propan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide |
| Molecular Formula | C24H23N5O5S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H23N5O5S2/c1-34-14-20(26-22(30)19-8-11-29(13-19)36(2,32)33)23(31)28-24-27-21(15-35-24)18-5-3-4-17(12-18)16-6-9-25-10-7-16/h3-13,15,20H,14H2,1-2H3,(H,26,30)(H,27,28,31)/t20-/m0/s1 |
| InChIKey | AXMLAOCXALIIRY-FQEVSTJZSA-N |
| SMILES | COCC(C(=O)NC1=NC(=CS1)C2=CC=CC(=C2)C3=CC=NC=C3)NC(=O)C4=CN(C=C4)S(=O)(=O)C |
| Reference | [1]. Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1. |
