FIDAS-5

• CAT Number: I015488
• CAS Number: 1391934-98-7
• Molecular Formula: C₁₅H₁₃ClFN
• Molecular Weight: 261.72
• Purity: ≥95%
• Target: Metabolic Enzyme/Protease

FIDAS-5(CAT: I015488) is a potent and orally active inhibitor of methionine S-adenosyltransferase 2A (MAT2A). MAT2A is an enzyme involved in the biosynthesis of S-adenosylmethionine (SAM), which is an essential methyl donor for various cellular processes. Inhibition of MAT2A can disrupt the SAM pool, leading to alterations in cellular methylation patterns and potential therapeutic effects. FIDAS-5 has shown promise as a MAT2A inhibitor and may have applications in cancer therapy and other diseases where targeting SAM metabolism is beneficial.

Reference

[1]. Zhang W, et al. Fluorinated N,N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A. ACS Chem Biol. 2013 Apr 19;8(4):796-803.