For research use only. Not for therapeutic Use.
Filipin Complex（Cat No.:M016531）is a potent polyene antibiotic derived from Streptomyces filipinensis, commonly used in biochemical and pharmaceutical research. Composed of a mixture of filipins, it binds specifically to cholesterol in cell membranes, making it invaluable for studying lipid membranes, cholesterol-rich domains, and membrane fluidity. Filipin Complex is often used in fluorescence microscopy for visualizing lipid distribution and studying cholesterol-related processes. Its ability to selectively bind cholesterol also makes it a useful tool for investigating lipid raft structures and cholesterol-dependent cellular processes in both basic and applied research.
| Catalog Number | M016531 |
| CAS Number | 11078-21-0 |
| Synonyms | 14-deoxylagosin;filimirasin;filmirisin;FILIPIN;FILIPIN COMPLEX;filipin complex from streptomyces filipinensis;FILIPIN COMPLEX FROM STREPTOMYCES & |
| Molecular Formula | C35H58O11 |
| Purity | ≥95% |
| Target | Fungal |
| Storage | -20°C |
| IUPAC Name | (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one |
| InChI | InChI=1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14+/t24-,25+,26-,27+,28-,29+,30+,31-,32+,33+,34-/m1/s1 |
| InChIKey | IMQSIXYSKPIGPD-YQRUMEKGSA-N |
| SMILES | CCCCC[C@H]([C@@H]1[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@@H](/C(=C/C=C/C=C/C=C/C=C/[C@@H]([C@H](OC1=O)C)O)/C)O)O)O)O)O)O)O)O |
| Reference | Filipin, an antifungal antibiotic: Isolation and properties. Whitfield G.B. et al. J. Am. Chem. Soc. 1955, 77, 4799.<br /> |
