Firefly luciferase-IN-1

• CAT Number: I040686
• CAS Number: 2765796-41-4
• Molecular Formula: C19H16O3
• Molecular Weight: 292.33
• Purity: ≥95%
• Synonyms: (6E)-6-[(4-methylphenyl)methylidene]-5-oxo-7,8-dihydronaphthalene-2-carboxylic acid
• InChI: InChI=1S/C19H16O3/c1-12-2-4-13(5-3-12)10-15-7-6-14-11-16(19(21)22)8-9-17(14)18(15)20/h2-5,8-11H,6-7H2,1H3,(H,21,22)/b15-10+
• InChIKey: HEEMJVLKXPNKTL-XNTDXEJSSA-N
• SMILES: CC1=CC=C(C=C1)C=C2CCC3=C(C2=O)C=CC(=C3)C(=O)O

Firefly luciferase-IN-1 (compound 48) is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM[1].

Reference

[1]. Li Y, et al. Identification of 2-Benzylidene-tetralone Derivatives as Highly Potent and Reversible Firefly Luciferase Inhibitors. ACS Med Chem Lett. 2022 Jan 20;13(2):304-311.
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