FK-3657

• CAT Number: I012638
• CAS Number: 167838-64-4
• Molecular Formula: C30H27Cl2N5O4
• Molecular Weight: 592.48
• Purity: ≥95%
• Synonyms: FR-173657; (E)-3-(6-Acetamido-3-pyridyl)-[N-[2,4-dichloro-3-[(2-methyl-8-quinolinyl)oxymethyl]phenyl]-N-methylaminocarbonylmethyl]acrylamide
• Target: Bradykinin Receptor
• IUPAC Name: (E)-3-(6-acetamidopyridin-3-yl)-N-[2-[2,4-dichloro-N-methyl-3-[(2-methylquinolin-8-yl)oxymethyl]anilino]-2-oxoethyl]prop-2-enamide
• InChI: InChI=1S/C30H27Cl2N5O4/c1-18-7-10-21-5-4-6-25(30(21)35-18)41-17-22-23(31)11-12-24(29(22)32)37(3)28(40)16-34-27(39)14-9-20-8-13-26(33-15-20)36-19(2)38/h4-15H,16-17H2,1-3H3,(H,34,39)(H,33,36,38)/b14-9+
• InChIKey: XCKWRUGRUFVXGC-NTEUORMPSA-N
• SMILES: CC1=NC2=C(C=CC=C2OCC3=C(C=CC(=C3Cl)N(C)C(=O)CNC(=O)C=CC4=CN=C(C=C4)NC(=O)C)Cl)C=C1

FK-3657(CAT: I012638) is a synthetic compound recognized for its role as an immunomodulatory agent, particularly in the modulation of T-cell responses. It has been studied for its potential applications in autoimmune diseases and transplant medicine due to its ability to regulate immune system activity, potentially reducing the risk of transplant rejection or mitigating autoimmune responses. FK-3657 is often utilized in research to investigate the mechanisms of immune tolerance, the development of novel immunosuppressive therapies, and the therapeutic management of immune-related disorders. Researchers in immunology and pharmacology leverage FK-3657 to explore its efficacy and safety in various preclinical models, aiming to develop innovative treatments for immune system modulation.