Flecainide-d4 Acetate [bis(2,2,2-trifluoroethoxy-1,1-d2)]

• CAT Number: R066526
• CAS Number: 1276197-21-7
• Molecular Formula: C19H24F6N2O5
• Molecular Weight: 478.425
• Purity: ≥95%
• Synonyms: N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide Acetate
• Target: Sodium Channel
• Storage: RT
• Related CAS: 1276197-20-6(base)
• IUPAC Name: acetic acid;2,5-bis(1,1-dideuterio-2,2,2-trifluoroethoxy)-N-(piperidin-2-ylmethyl)benzamide
• InChI: InChI=1S/C17H20F6N2O3.C2H4O2/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11;1-2(3)4/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26);1H3,(H,3,4)/i9D2,10D2
• InChIKey: RKXNZRPQSOPPRN-PQDNHERISA-N
• SMILES: CC(=O)O.C1CCNC(C1)CNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F

Flecainide-d4 Acetate [bis(2,2,2-trifluoroethoxy-1,1-d2)] is a deuterated form of flecainide acetate, a class 1c antiarrhythmic agent used to treat irregular heartbeats. In this compound, four hydrogen atoms are replaced with deuterium, and the trifluoroethoxy groups also contain deuterium, enhancing its utility as an internal standard. It is employed in mass spectrometry and NMR spectroscopy to ensure precise quantification and structural analysis of flecainide. In pharmaceutical chemistry, it supports studies on drug metabolism, pharmacokinetics, and pharmacodynamics. Its deuterium labeling improves the accuracy and reliability of analytical methods, crucial for evaluating drug behavior and interactions.