Fleroxacin

• CAT Number: A000230
• CAS Number: 79660-72-3
• Molecular Formula: C17H18F3N3O3
• Molecular Weight: 369.34
• Purity: ≥95%
• Synonyms: 79660-72-3; Megalone; Fleroxacino; Fleroxacinum; Fleroxicin
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• InChI: InChI=1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26)
• InChIKey: XBJBPGROQZJDOJ-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CCF)F

Fleroxacin（Cat No.:A000230）is a broad-spectrum fluoroquinolone antibiotic effective against a variety of Gram-negative and some Gram-positive bacteria. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair, leading to bacterial cell death. Fleroxacin is used primarily to treat respiratory, urinary tract, and gastrointestinal infections. Its high oral bioavailability and tissue penetration make it suitable for systemic infections. Fleroxacin is particularly valuable in studies of drug-resistant bacterial strains, supporting advancements in antibiotic therapy and resistance management in clinical and research settings.

Reference

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