FLLL31

• CAT Number: I006804
• CAS Number: 52328-97-9
• Molecular Formula: C25H28O6
• Molecular Weight: 424.49
• Purity: ≥95%
• Synonyms: FLLL31; FLLL 31; FLLL-31.;(1E,6E)-1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione
• Target: Stem Cell/Wnt
• Solubility: Soluble in DMSO, not in water
• Storage: 2-8°C
• IUPAC Name: (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione
• InChI: InChI=1S/C25H28O6/c1-25(2,23(26)13-9-17-7-11-19(28-3)21(15-17)30-5)24(27)14-10-18-8-12-20(29-4)22(16-18)31-6/h7-16H,1-6H3/b13-9+,14-10+
• InChIKey: VMMZAMVBGQWOHT-UTLPMFLDSA-N
• SMILES: CC(C)(C(=O)C=CC1=CC(=C(C=C1)OC)OC)C(=O)C=CC2=CC(=C(C=C2)OC)OC

FLLL31（Cat No.:I006804） is a curcumin analog that acts as a potent inhibitor of STAT3, a transcription factor involved in cancer progression. It effectively inhibits the phosphorylation, DNA binding activity, and transactivation of STAT3 in vitro. FLLL31 also demonstrates inhibitory effects on colony formation in soft agar and cell invasion. Additionally, it shows synergistic effects when combined with the anti-cancer drug doxorubicin against breast cancer cells.