Flomoxef

• CAT Number: R055917
• CAS Number: 99665-00-6
• Molecular Formula: C15H18F2N6O7S2
• Molecular Weight: 496.46
• Purity: ≥95%
• Synonyms: (6R,7R)-7-[[[(Difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R-cis)7-[[[(Difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tet
• Storage: -20°C
• IUPAC Name: (6R,7R)-7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• InChI: InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1
• InChIKey: UHRBTBZOWWGKMK-DOMZBBRYSA-N
• SMILES: CO[C@@]1([C@@H]2N(C1=O)C(=C(CO2)CSC3=NN=NN3CCO)C(=O)O)NC(=O)CSC(F)F

Flomoxef（Cat No.:R055917）is an oxacephem antibiotic with a broad spectrum, particularly effective against Gram-negative bacteria, including Escherichia coli and Klebsiella species, as well as some Gram-positive pathogens. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death. Flomoxef is often used to treat respiratory, urinary, and abdominal infections, and is especially valued in hospital settings for treating severe infections. Its stability against beta-lactamase enzymes enhances its efficacy against resistant strains, making it a valuable option in the fight against difficult-to-treat bacterial infections.